Polysubstituted and ring-fused pyridazine systems from tetrafluoropyridazine
نویسندگان
چکیده
منابع مشابه
Fused-Ring Oxazolopyrrolopyridopyrimidine Systems with Gram-Negative Activity
Fused polyheterocyclic derivatives are available by annulation of a tetramate scaffold, and been shown to have antibacterial activity against a Gram-negative, but not a Gram-positive, bacterial strain. While the activity is not potent, these systems are structurally novel showing, in particular, a high level of polarity, and offer potential for the optimization of antibacterial activity.
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ژورنال
عنوان ژورنال: Tetrahedron
سال: 2017
ISSN: 0040-4020
DOI: 10.1016/j.tet.2016.12.006